Researchers have experimentally implemented compact quantum circuits that simulate the state-transfer interference underlying three- and four-level chiral-resolution protocols. These models, encoded in a two-qubit register, simulate the enantiomer-dependent sign of one of the couplings. In the four-level circuit, this is achieved by a conditional-phase operation, while in the three-level circuit, the sign of a final rotation is used. Experiments performed on an IBM quantum processor have shown that both circuits produce the expected enantiomer-dependent output states with probabilities of nearly 98%.